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Towa (Japan) Sildenafil Citrate Tablets (Sildenafil OD Tablets) 50mg VI, 20 Tablets—Male Erectile Dysfunction Treatment, Delayed Ejaculation, Prolonged Erection, Adult Erectile Dysfunction Treatment and Enhancement

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Sildenafil Sildenafil OD Tablets 50 mg VI "Towa"
SILDENAFIL OD TABLETS 50 mg VI “TOWA”

Package Insert No. 259000AF3027_1_09 | Company Code 480235
Prepared in November 2023 (1st Edition)

Erectile Dysfunction Treatment | Orally Disintegrating Tablets | Coffee/Lemon Flavor | Not listed in the drug price reference

Lemon Viagra, Donghe, Sildenafil OD

Product Details / Approvals, etc.

Japan Standard Commodity Classification Code 87259
Pharmacological Classification Name Erectile Dysfunction Treatment
General Name Sildenafil Citrate Orally Disintegrating Tablets
50mg Sildenafil OD Tablets 50 mg VI "Towa"
YJ 259000AF3027
Approved 22600AMX00588
On Sale: May 2014
Storage Instructions / Expiration Date Store at room temperature / 5 years
Regulatory Classification –
Manufacturing and Sales Yuan Tohwa Pharmaceutical Co., Ltd.
2-11 Shinbashi-cho, Kadoma City, Osaka Prefecture
Packaging 20 tablets [10 tablets × 2 PTPs]
60 tablets [10 tablets × 6 PTPs]
(Coffee flavor, lemon flavor)
Insurance Benefits Not listed in the drug pricing guidelines; therefore, not covered by insurance.
Shipping method Direct overseas shipping (Direct shipping from Japan)
Preparation and shipping time Once payment and prescription eligibility have been verified, orders are typically shipped within 4 to 7 business days.

1. Warning

Concomitant use with nitrates or nitric oxide (NO) donors may cause excessive hypotension. Ensure that these agents are not being used before administration, and avoid concomitant use during and after administration.

There have been reports of serious cardiovascular adverse events, including myocardial infarction with fatal outcomes. Before administration, thoroughly assess whether the patient has any cardiovascular disorders.

2. Product Characteristics and Mechanism of Action (18.)

By selectively inhibiting PDE5 in the corpus cavernosum of the penis, it reduces the breakdown of cGMP stimulated by NO, causing relaxation of the corpus cavernosum smooth muscle and increased blood flow, thereby facilitating and maintaining an erection. The IC₅₀ for human corpus cavernosum PDE5 is50 3.5 nmol/L. Orally disintegrating tablets; allow to dissolve in the mouth before swallowing. Not an aphrodisiac or libido enhancer.

3. Specifications and Properties (3.2)

White orally disintegrating tablets with a score line. 10.0 mm in diameter, 4.5 mm thick, and weighing 340 mg. The front is labeled “シルデナ50,” and the back is labeled “シルデナフィル OD 50 トーワ.”

4. Ingredient Information (3.1/19.)

Each tablet contains 70.23 mg of citrate (equivalent to 50 mg of sildenafil). Contains aspartame (an L-phenylalanine derivative) and flavoring.

19. Molecular formula C22H30N6O4S・C6H8O7 Molecular weight 666.70.

Structural Formula

5. Indications and Usage (4./5.)

4. Erectile dysfunction (patients who are unable to achieve and maintain an erection sufficient for satisfactory sexual intercourse)

Before administration, a medical history review and physical examination must be conducted; this product is intended only for patients who, following an objective diagnosis, require clinical treatment. This product is not an aphrodisiac or a libido enhancer.

6. Dosage and Administration (6./7.)

The usual adult dose is 25 mg to 50 mg of sildenafil once daily, taken orally approximately 1 hour before sexual activity. This product is available in 50 mg tablets, which can be split along the score line to obtain a dose of approximately 25 mg.

For elderly patients (65 years of age or older), patients with hepatic impairment, and patients with severe renal impairment (Ccr < 30 mL/min), the starting dose is 25 mg.

Take only once a day, with at least 24 hours between doses. Taking this medication with food may delay its onset of action.

7. Precautions and Contraindications (2./8.)

2. Contraindications

  1. Allergy to any ingredient in this product
  2. Currently using nitric acid agents or NO donors
  3. Individuals with cardiovascular conditions or other medical conditions that make sexual activity inadvisable
  4. Severe liver dysfunction
  5. Hypotension (170 or diastolic blood pressure >100 mmHg at rest)
  6. History of ischemic stroke, hemorrhagic stroke, or myocardial infarction within the past 6 months
  7. Retinitis Pigmentosa
  8. Currently taking amiodarone orally
  9. Currently taking the sGC agonist riociguat

Seek immediate medical attention if an erection lasts for more than 4 hours. If you experience a sudden decrease in vision or vision loss, stop taking the medication and see an ophthalmologist immediately.

Bioequivalence with Viagra 50 mg:

BE1

BE2

22–26. Other Official Information

22. 20 tablets / 60 tablets PTP (coffee flavor, lemon flavor)

24. Toho Pharmaceutical Co., Ltd., Academic Department, DI Center, 0120-108-932, FAX 06-7177-7379

25. This product is not covered by insurance (it is not listed in the drug price guidelines).

26. Manufacturer and Distributor: Towa Pharmaceutical Co., Ltd., 2-11 Shinbashi-cho, Kadoma City, Osaka Prefecture

※ This page was translated by Hkeemall based on PMDA Package Insert 259000AF3027_1_09; it is not a substitute for a doctor’s prescription or the original Japanese version.
Enter "PMDA Package Insert Information" and search for "Sildenafil OD Tablets VI, Towa" to view the original version.

[Disclaimer]

  1. The information regarding medications, treatments, or health management contained in this article is compiled from international authoritative medical journals and official clinical literature, and is intended for general science and educational reference only.
  2. The indications, side effects, and contraindications of related medications may vary depending on national regulations and individual physical conditions. Do not blindly take medication on your own or change your treatment plan.
  3. The author and publishing platform assume no legal liability for any medical delays, adverse reactions, or direct or indirect losses caused by the use of the information in this article. All medical decisions should be discussed with your attending physician before being made.

Additional information

Specifications

Towa Sildenafil Sildenafil OD Tablets 50 mg

1 review for 日本東和 Sildenafil 西地那非檸檬酸鹽片 シルデナフィルOD錠 50mgVI 20錠 男性助勃 延時增强 久硬不射 成人助勃增强

5.00

Average of 1 review

  1. Ryan Ho –

    Took half a pill and it got hard as a rock, lasted long and didn't ejaculate easily. The effect is really solid, best value for money!

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