{"id":5257,"date":"2026-08-22T11:15:22","date_gmt":"2026-08-22T11:15:22","guid":{"rendered":"https:\/\/hkeemall.com\/?p=5257"},"modified":"2026-08-22T11:20:28","modified_gmt":"2026-08-22T11:20:28","slug":"1787397326-2","status":"publish","type":"post","link":"https:\/\/hkeemall.com\/en\/1787397326-2\/","title":{"rendered":"\ud83d\udc8a The \"hidden skills\" of tirzepatide: Besides weight loss, what else can it improve"},"content":{"rendered":"

\u8a31\u591a\u4eba\u5c0d\u66ff\u897f\u5e15\u80bd\u7684\u5370\u50cf\u9084\u505c\u7559\u5728\u300c\u6e1b\u80a5\u91dd\u300d\u4e0a\u3002\u6c92\u932f\uff0c\u5b83\u7684\u6e1b\u91cd\u6548\u679c\u78ba\u5be6\u7206\u70b8\u2014\u201472\u5468\u5e73\u5747\u6e1b\u91cd\u8d8520%\uff0c\u76f4\u63a5\u628a\u53f8\u7f8e\u683c\u9b6f\u80bd\u62c9\u4e0b\u795e\u58c7\u3002\u4f46\u5982\u679c\u4f60\u53ea\u628a\u5b83\u7576\u6e1b\u80a5\u85e5\uff0c\u5c31\u771f\u7684\u4f4e\u4f30\u5b83\u4e86\u3002<\/span><\/span><\/p>\n

\u904e\u53bb\u4e00\u5e74\uff0c\u4e00\u7cfb\u5217\u91cd\u78c5\u7814\u7a76\u63ed\u958b\u4e86\u66ff\u897f\u5e15\u80bd\u7684\u300c\u96b1\u85cf\u8eab\u5206\u300d\uff1a<\/span><\/span>\u5b83\u4e0d\u50c5\u662f\u6e1b\u91cd\u5de5\u5177\uff0c\u4e5f\u662f\u4e00\u53f0\u5168\u8eab\u4ee3\u8b1d\u8abf\u7bc0\u5668<\/span><\/span>\u3002\u4eca\u5929\u5c31\u4f86\u76e4\u9ede\u4e00\u4e0b\uff0c\u9664\u4e86\u6e1b\u80a5\uff0c\u5b83\u9084\u80fd\u5e6b\u4f60\u505a\u4ec0\u9ebc\u3002<\/span><\/span><\/p>\n

\u2764\ufe0f \u8b77\u5fc3\uff1a\u5fc3\u81df\u8870\u7aed\u4f4f\u9662\u98a8\u96aa\u76f4\u964d58%<\/span><\/span><\/h3>\n

2025\u5e74\u767c\u8868\u5728\u300aJAMA\u300b\u4e0a\u7684\u4e00\u9805\u7814\u7a76\uff0c\u4ee5\u8fd110\u842c\u540d\u60a3\u8005\u7684\u771f\u5be6\u6578\u64da\u7d66\u51fa\u4e86\u5be6\u9318\u3002\u8207\u5b89\u6170\u5291\u76f8\u6bd4\uff0c\u66ff\u897f\u5e15\u80bd\u4f7f\u5c04\u8840\u5206\u6578\u4fdd\u7559\u7684\u5fc3\u81df\u8870\u7aed\uff08HFpEF\uff09\u60a3\u8005\u7684\u5fc3\u81df\u8870\u7aed\u4f4f\u9662\u6216\u5168\u56e0\u6b7b\u4ea1\u98a8\u96aa<\/span><\/span>\u964d\u4f4e\u4e8658%\u00a0<\/span><\/span>\u3002\u800c\u9019\u7a2e\u4fdd\u8b77\u6548\u679c\u5728\u4e0d\u540c\u5e74\u9f61\u3001\u6027\u5225\u7684\u60a3\u8005\u4e2d\u5168\u90fd\u6210\u7acb\u3002<\/span><\/span><\/p>\n

2026\u5e74\u7684\u4e00\u9805\u7cfb\u7d71\u6027\u56de\u9867\u548cMeta\u5206\u6790\u4e5f\u8b49\u5be6\uff0c\u66ff\u897f\u5e15\u80bd\u8207\u4e3b\u8981\u4e0d\u826f\u5fc3\u8840\u7ba1\u4e8b\u4ef6\uff08MACE\uff09\u98a8\u96aa\u964d\u4f4e\u6709\u95dc\uff08OR 0.87\uff09\uff0c\u4e26\u4e14\u8207\u5168\u56e0\u6b7b\u4ea1\u98a8\u96aa\u964d\u4f4e\u6709\u95dc\uff08OR 0.84\uff09\u3002\u66f4\u503c\u5f97\u6ce8\u610f\u7684\u662f\uff0c\u66ff\u897f\u5e15\u80bd\u7684\u5291\u91cf\u6bcf\u589e\u52a01mg\uff0cMACE\u98a8\u96aa\u5c31\u6703\u964d\u4f4e2.8%\u2014\u2014\u4e5f\u5c31\u662f\u8aaa\uff0c\u6548\u679c\u662f\u300c\u5291\u91cf\u4f9d\u8cf4\u300d\u7684\uff0c\u8db3\u91cf\u4f7f\u7528\u7372\u76ca\u66f4\u5927\u3002<\/span><\/span><\/p>\n

\u6b64\u5916\uff0cSUMMIT\u8a66\u9a57\u7684\u9810\u8a2d\u5206\u6790\u4e5f\u767c\u73fe\uff0c\u7121\u8ad6\u60a3\u8005\u662f\u5426\u5408\u4f75\u7b2c2\u578b\u7cd6\u5c3f\u75c5\uff0c\u66ff\u897f\u5e15\u80bd\u90fd\u80fd\u4e00\u81f4\u5730\u6539\u5584\u5fc3\u81df\u8870\u7aed\u75c7\u72c0\u548c\u529f\u80fd\u3002\u6240\u4ee5\uff0c\u5b83\u8b77\u5fc3\u4e0d\u6311\u4eba\u3002<\/span><\/span><\/p>\n

\ud83d\ude34 \u6cbb\u6253\u9f3e\uff1a\u9996\u500b\u6838\u51c6\u7684OSA\u85e5\u7269<\/span><\/span><\/h3>\n

2024\u5e7412\u6708\uff0c\u7f8e\u570bFDA\u6b63\u5f0f\u6838\u51c6\u66ff\u897f\u5e15\u80bd\u7528\u65bc\u6cbb\u7642<\/span><\/span>\u4e2d\u91cd\u5ea6\u963b\u585e\u6027\u7761\u7720\u547c\u5438\u4e2d\u6b62\u75c7\uff08OSA\uff09<\/span><\/span>\uff0d\u9019\u662f\u5168\u7403\u9996\u500b\u6838\u51c6\u6cbb\u7642OSA\u7684\u85e5\u7269\u3002<\/span><\/span><\/p>\n

SURMOUNT-OSA\u7814\u7a76\u7684\u6578\u64da\u76f8\u7576\u786c\u6838\uff1a\u672a\u63a5\u53d7PAP\u6cbb\u7642\u7684\u60a3\u8005\u4e2d\uff0c\u66ff\u897f\u5e15\u80bd\u7d44AHI\u6307\u6578\uff08\u547c\u5438\u66ab\u505c\u6b21\u6578\/\u5c0f\u6642\uff09<\/span><\/span>\u5e73\u5747\u6e1b\u5c11\u4e8625.3\u6b21\/\u5c0f\u6642<\/span><\/span>\uff0c\u800c\u5b89\u6170\u5291\u7d44\u53ea\u6e1b\u5c11\u4e865.3\u6b21\/\u5c0f\u6642\u3002\u63a5\u53d7PAP\u6cbb\u7642\u7684\u60a3\u8005\u7d44\uff0c\u66ff\u897f\u5e15\u80bd\u7684\u6548\u679c\u66f4\u660e\u986f\uff0dAHI\u6307\u6578\u6e1b\u5c11\u4e8629.3\u6b21\/\u5c0f\u6642\u3002<\/span><\/span><\/p>\n

\u5728SURMOUNT-OSA\u8a66\u9a57\u4e2d\uff0c\u66ff\u897f\u5e15\u80bd\u8b93\u60a3\u8005\u9ad4\u91cd\u6e1b\u8f15\u4e8618%\u81f320%\uff0cAHI\u4e8b\u4ef6\u964d\u4f4e\u4e86\u7d0420\u81f324\u6b21\/\u5c0f\u6642\uff0c\u540c\u6642\u6539\u5584\u4e86\u8840\u58d3\u548c\u767c\u708e\u6a19\u8a18\u3002\u5b83\u7684\u4f5c\u7528\u6a5f\u5236\u4e0d\u53ea\u662f\u201c\u6e1b\u91cd\u201d\uff0c\u9084\u6d89\u53ca\u8abf\u7bc0\u8102\u80aa\u5206\u4f48\u548c\u81ea\u4e3b\u795e\u7d93\u529f\u80fd\uff0c\u5f9e\u800c\u6539\u5584\u7761\u7720\u547c\u5438\u6a5f\u5236\u3002<\/span><\/span><\/p>\n

\ud83e\udec1 \u8b77\u809d\uff1aMASH\u7de9\u89e3\u7387\u9ad8\u905462%<\/span><\/span><\/h3>\n

\u4ee3\u8b1d\u529f\u80fd\u969c\u7919\u76f8\u95dc\u8102\u80aa\u6027\u809d\u708e\uff08MASH\uff0c\u66fe\u7528\u540dNASH\uff09\u662f\u6700\u5e38\u898b\u7684\u809d\u75c5\u4e4b\u4e00\uff0c2025\u5e74NEJM\u767c\u8868\u7684SYNERGY-NASH\u7814\u7a76\u7d66\u51fa\u4e86\u4ee4\u4eba\u632f\u596e\u7684\u7d50\u679c\u3002<\/span><\/span><\/p>\n

\u5728\u4f34\u6709\u4e2d\u5ea6\u6216\u91cd\u5ea6\u809d\u7e96\u7dad\u5316\u7684MASH\u60a3\u8005\u4e2d\uff0c<\/span><\/span>62%<\/span><\/span>\u768415mg\u66ff\u897f\u5e15\u80bd\u7d44\u60a3\u8005\u5be6\u73fe\u4e86MASH\u7de9\u89e3\u4e14\u7121\u7e96\u7dad\u5316\u60e1\u5316\uff0c\u800c\u5b89\u6170\u5291\u7d44\u53ea\u6709<\/span>10%\u00a0<\/span>\u3002\u4e09\u500b\u5291\u91cf\u7d44\uff085mg\u300110mg\u300115mg\uff09\u7684\u7de9\u89e3\u7387\u90fd\u986f\u8457\u512a\u65bc\u5b89\u6170\u5291\uff08P\u7686<0.001\uff09\u3002\u6b64\u5916\uff0c\u81f3\u5c11\u6539\u5584\u4e00\u500b\u7e96\u7dad\u5316\u5206\u671f\u7684\u6bd4\u4f8b\uff0c\u66ff\u897f\u5e15\u80bd\u7d44\u572851%-55%\u4e4b\u9593\uff0c\u5b89\u6170\u5291\u7d44\u53ea\u670930%\u3002<\/span><\/span><\/p>\n

2026\u5e74\u767c\u8868\u7684\u53e6\u4e00\u9805\u5927\u898f\u6a21Meta\u5206\u6790\uff08\u6db5\u84cb17\u9805RCT\uff0c\u8d8525000\u540d\u53c3\u8207\u8005\uff09\u4e5f\u8b49\u5be6\uff0c\u66ff\u897f\u5e15\u80bd\u5728MASH\u7de9\u89e3\u65b9\u9762\u7684\u76f8\u5c0d\u98a8\u96aa\u6bd4\uff08RR\uff09\u9ad8\u9054<\/span><\/span>5.33\u00a0<\/span><\/span>\u3002\u60a3\u8005\u809d\u9175\u7d20ALT\u548cAST\u4e5f\u986f\u8457\u4e0b\u964d\uff08\u9577\u671f\u4f7f\u7528\u8005\u964d\u4f4e\u7d0413%-20%\uff09\u3002<\/span><\/span><\/p>\n

\ud83e\ude78 \u964d\u8840\u8102+\u8b77\u814e<\/span><\/span><\/h3>\n

\u591a\u9805\u7814\u7a76\u8b49\u5be6\uff0c\u66ff\u897f\u5e15\u80bd\u9084\u80fd\u540c\u6b65\u6539\u5584\u8840\u8102\u548c\u814e\u529f\u80fd\u3002<\/span><\/span><\/p>\n

\u8840\u8102\u65b9\u9762<\/span><\/span>\uff0c\u4e09\u9178\u7518\u6cb9\u916f\u5e73\u5747\u964d\u4f4e<\/span><\/span>19.6%\u00a0<\/span><\/span>\uff0c\u7e3d\u81bd\u56fa\u9187\u964d\u4f4e<\/span><\/span>18.7%\u00a0<\/span><\/span>\uff0c\u300c\u58de\u81bd\u56fa\u9187\u300dLDL-C\u964d\u4f4e<\/span><\/span>30.5%\u00a0<\/span><\/span>\u3002\u6536\u7e2e\u58d3\u5e73\u5747\u964d\u4f4e\u7d04<\/span><\/span>5.8 mmHg\u00a0<\/span><\/span>\u3002<\/span><\/span><\/p>\n

\u814e\u81df\u4fdd\u8b77<\/span><\/span>\u65b9\u9762\uff0c\u5728\u4e00\u9805\u963f\u806f\u914b\u7684\u771f\u5be6\u4e16\u754c\u7814\u7a76\u4e2d\uff0c\u9577\u671f\u4f7f\u7528\u66ff\u897f\u5e15\u80bd\uff08>1\u5e74\uff09\u7684\u60a3\u8005\u814e\u529f\u80fd\u6307\u6a19\u986f\u8457\u6539\u5584\uff1a\u4f30\u7b97\u814e\u5c0f\u7403\u6ffe\u904e\u7387\uff08eGFR\uff09<\/span><\/span>\u589e\u52a0\u4e863.2%\u00a0<\/span><\/span>\uff0c\u8840\u808c\u9178\u9150<\/span><\/span>\u4e0b\u964d\u4e866.6%\u00a0<\/span><\/span>\uff0c\u8840\u4e2d\u5c3f\u7d20\u6c2e<\/span><\/span>\u4e0b\u964d\u4e867.8%\u00a0<\/span><\/span>\u3002 2026\u5e74\u7684Meta\u5206\u6790\u540c\u6a23\u8b49\u5be6\uff0c\u66ff\u897f\u5e15\u80bd\u6709\u52a9\u65bc<\/span><\/span>\u5ef6\u7de9eGFR\u4e0b\u964d<\/span><\/span>\uff08\u6bcf\u5e74+1.5 mL\/min\uff09\u3002<\/span><\/span><\/p>\n

\u6b64\u5916\uff0c2026\u5e74\u555f\u52d5\u7684TEAR-AF\u8a66\u9a57\uff0c\u6b63\u5728\u7814\u7a76\u66ff\u897f\u5e15\u80bd\u80fd\u5426\u6e1b\u5c11\u80a5\u80d6\u5408\u4f75\u5fc3\u623f\u986b\u52d5\u60a3\u8005\u6d88\u878d\u8853\u5f8c\u7684\u5fa9\u767c\u7387\uff08\u8a08\u756b\u7d0d\u5165710\u540d\u60a3\u8005\uff09\u3002<\/span><\/span><\/p>\n

\u26a0\ufe0f<\/span><\/span>\u66ff\u897f\u5e15\u80bd\u6b63\u5f9e\u300c\u6e1b\u80a5\u85e5\u300d\u9032\u5316\u70ba\u300c<\/span><\/span>\u5168\u9762\u4ee3\u8b1d\u4fdd\u8b77\u5291<\/span><\/span>\u300d\u3002\u5b83\u4e0d\u50c5\u80fd\u8b93\u4f60\u7626\uff0c\u9084\u80fd\u8b77\u5fc3\u3001\u6cbb\u6253\u9f3e\u3001\u6539\u5584\u8102\u80aa\u809d\u3001\u964d\u8840\u8102\u3001\u8b77\u814e\u2014\u2014\u582a\u7a31\u4ee3\u8b1d\u9818\u57df\u7684\u300c\u8de8\u754c\u5168\u80fd\u9078\u624b\u300d\u3002<\/span><\/span><\/h3>\n

\u4f46\u5b83\u4f9d\u7136\u662f<\/span><\/span>\u8655\u65b9\u85e5<\/span><\/span>\uff0c\u5fc5\u9808\u5728\u91ab\u751f\u6307\u5c0e\u4e0b\u4f7f\u7528\u3002\u6709\u7532\u72c0\u817a\u9ad3\u6a23\u764c\u75c5\u53f2\u6216\u5bb6\u65cf\u53f2\u7684\u4eba<\/span><\/span>\u7d55\u5c0d\u7981\u7528<\/span><\/span>\u3002<\/span><\/span><\/p>","protected":false},"excerpt":{"rendered":"

Many people still think of tezipepet as a \u201cweight-loss shot.\u201d That\u2019s right\u2014its weight-loss effects are truly explosive: an average weight loss of over 20% over 72 weeks, putting Semege<\/p>\n

Read More <\/i><\/a><\/div>","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_thinkrank_schema_form_data":"","_thinkrank_selected_schema_type":"","_thinkrank_additional_schemas":"","_thinkrank_canonical_url":"","_thinkrank_og_title":"","_thinkrank_og_description":"","_thinkrank_og_image":"","_thinkrank_twitter_title":"","_thinkrank_twitter_description":"","_thinkrank_twitter_image":"","_thinkrank_imported_from":"","_thinkrank_focus_keywords":["HKEEMALL"],"_thinkrank_focus_keyword":"HKEEMALL","_thinkrank_robots_meta_enabled":0,"_thinkrank_robots_meta":"[]","_thinkrank_advanced_robots_meta":"[]","_thinkrank_primary_category":0,"footnotes":""},"categories":[1],"tags":[176],"class_list":["post-5257","post","type-post","status-publish","format-standard","hentry","category-news","tag-hkeemall"],"_links":{"self":[{"href":"https:\/\/hkeemall.com\/en\/wp-json\/wp\/v2\/posts\/5257","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/hkeemall.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/hkeemall.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/hkeemall.com\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/hkeemall.com\/en\/wp-json\/wp\/v2\/comments?post=5257"}],"version-history":[{"count":2,"href":"https:\/\/hkeemall.com\/en\/wp-json\/wp\/v2\/posts\/5257\/revisions"}],"predecessor-version":[{"id":5259,"href":"https:\/\/hkeemall.com\/en\/wp-json\/wp\/v2\/posts\/5257\/revisions\/5259"}],"wp:attachment":[{"href":"https:\/\/hkeemall.com\/en\/wp-json\/wp\/v2\/media?parent=5257"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/hkeemall.com\/en\/wp-json\/wp\/v2\/categories?post=5257"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/hkeemall.com\/en\/wp-json\/wp\/v2\/tags?post=5257"}],"curies":[{"name":"Well played","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}